After first noting that I seek to broaden the definition of science fiction to a little more loosely defined speculative fiction, this essay explores four different ways in which fiction can work together with both the sciences and the philosophy of perception. This cooperation is needed because there is much about the sensory worlds of humans and non-human animals of which we continue to be ignorant. First, speculative fiction can be a source of hypotheses about the nature of the senses. Second, it can help us understand the inner worlds of beings different from us. Third, speculative fiction often pushes us to investigate the ethical and social dimensions of sensory difference. Finally, speculative fiction can play an important role in reconciling our scientific understanding of the senses with a more commonsense understanding of same.